Comparing immune-tumor growth models with drug therapy using optimal control

By Martins, M.C.; Rocha, A.M.A.C.; Costa, M.F.P.; Fernandes, E.M.G&

AIP Conference Proceedings



In this paper we compare the dynamics of three tumor growth models that include an immune system and a drug administration therapy using optimal control. The objective is to minimize a combined function of the total of tumor cells over time and a chemotherapeutic drug administration.


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